Month: October 2017

October 2017 News

Posted by | Oct 27, 2017 | |

  Exciting news this month. I will start with the best. Clemastine fumarate, an over the counter antihistamine drug  used to relieve symptoms of allergies can successfully repair the myelin in people with MS. Yes, it works!  Previous studies found that clemastine fumarate can stimulate differentiation of oligodendrocyte precursor cells in vitro, in animal models, and in human cells. Clemastine made the headlines last year, as well, when another study was published. But now, this October 2017 study is the  first randomised controlled trial to document efficacy of a remyelinating drug for the treatment of chronic demyelinating injury in MS.  Ok, so clemastine fumarate is effective. How about its safety ? According to this study, fatigue was reported, but otherwise  no serious side effects. The dose used was 5.36 mg orally twice daily. What about the cost ? It is an old generation anti-histamine drug, therefore much cheaper than the current drugs for MS (which are immune-modulating and do not directly promote myelin repair, by the way).  I do expect more great news. While clemastine seems the best choice, several other drugs may help repair the myelin. I will review histamine as a brain neurotransmitter, histamine imbalances in MS, and why some anti-histamine drugs work, their pros and cons-in another article. Decreasing the inflammation and autoimmunity, optimizing the metabolism of sugar , the hormones and mitochondrial function would be very helpful  for myelin...

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How To Increase Dopamine – Best Dopamine Supplements and Meds

Posted by | Oct 27, 2017 | |

  Dopamine levels should be optimal, as both dopamine deficiency and dopamine excess can be detrimental. Read my other article about how important is dopamine for the brain, the low dopamine symptoms list  and the multiple sclerosis dopamine deficiency link.   Note: all the natural supplements and dietary changes described below would benefit everyone who wants a dopamine boost. They are also helpful for managing Parkinson’s  disease, since dopamine deficiency is the key problem in Parkinson’s. Some cases of MS had been associated with dopamine deficiency -not as severe as in Parkinson’s but this shortage in dopa levels still has to be improved. I am exploring here the best dopamine supplements, dietary and lifestyle changes  as well as the medications that increase dopamine.  You will find that  some supplements and therapies can help correct both dopamine and norepinephrine levels. Dopamine is a precursor of norepinephrine and both are involved in “fight or flight “reaction. Both dopamine and norepinephrine play a key role in your mood, cognitive function and attention. Dopamine is mostly involved in motivation/drive,  in  reward and pleasure behavior, appetite and sex control,  where norepinephrine boosts your energy levels, concentration and alertness.     Diet and Therapies that Boost Dopamine  Best Dopamine Supplements Medications That Increase Dopamine Coffee, Chocolate, Alcohol  and More   1. Diet and Lifestyle Changes To Increase Dopamine  :  A. Dietary changes Key ideas: Cut...

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L-Tyrosine Benefits

Posted by | Oct 22, 2017 | |

L-Tyrosine benefits are multiple, not just for your brain health, but also for the function of your immune system, hormones and your ability to cope with stress.   L-tyrosine Benefits -Summary : 1.Tyrosine Is a Precursor of Key Neurotransmitters 2.Tyrosine and Hormones 3.L-Tyrosine Is an Adaptogen (Helps You Cope With Stress) 4.L-Tyrosine For  Depression- Does it Work ? 5. L-Tyrosine As a Nootropic (Improves Mental Performance) 6.L-Tyrosine for Weight Loss, Blood Pressure and  Other Health Benefits In addition, learn about L-tyrosine dosage and L-tyrosine side effects 1.Tyrosine Is a Precursor Of Important  Neurotransmitters Tyrosine is an amino acid that body makes from phenylalanine. The neurotransmitters dopamine, norepinephrine and adrenaline are all made from tyrosine. Phenylalanine→ Tyrosine→ L-DOPA→ Dopamine→ Norepinephrine→ Epinephrine (Adrenaline) * *cofactors like vitamins and minerals are involved in this chain reaction Neurotransmitters help improve communication between brain cells, influence the mood and overall health . Using tyrosine supplements does help increase the levels of norepinephrine and dopamine in the brain [1]. MS had been associated with neurotransmitter imbalances, thus one more reason to improve the levels of these brain chemicals. Norepinephrine gives you energy and helps your brain fight degeneration and inflammation , and improves memory. MS is linked with norepinephrine deficiency. Dopamine makes you feel motivated, focused, controls movement and coordination. Influences sex hormones and thyroid hormones. Improves the communication between the immune system and nervous system and...

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Is Multiple Sclerosis Fatal ? What About Multiple Sclerosis Life Expectancy ?

Posted by | Oct 17, 2017 | |

  Is multiple sclerosis fatal? What about multiple sclerosis life expectancy ? It is absolutely normal  to ask yourself these questions. You likely thought about them  when you receive the diagnosis of MS. A disease is viewed as a threat to your health, and you life. The mind  is designed this way, it’s  wired to look at the worse case scenario, especially when under stress or receiving bad news. Key Points 1.Is Multiple Sclerosis Fatal? What About Multiple Sclerosis Life Expectancy ? 2.Lifespan Vs Healthspan – Which One Is More Important ? 3.A Different Answer (From a Different Perspective) To the Question- Is Multiple Sclerosis Fatal?   1.Is Multiple Sclerosis Fatal? What About Multiple Sclerosis Life Expectancy ? Some will ask the doctor, others will search “Dr. Google” to get the answer. Let me tell you something. Doctors aren’t  shy to tell you if a condition is fatal- if it is. Think heart attack, or anaphylactic shock. You get the warning about these conditions  as being fatal right away, the moment you open the first medical text-book or talk with an ER physician. On the other hand, MS is well-known  as a “chronic “ disease, that can be silent for decades, with relapses and remissions. Next you may look at the top 10 causes of death …guess what? MS is not on the list [1] .How about the top...

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Dopamine Deficiency. Low Dopamine Symptoms List

Posted by | Oct 14, 2017 | |

Most of us link dopamine deficiency with depression and Parkinson’s disease. Could dopamine deficiency be a root cause of other conditions such as weight gain, diabetes, MS and other autoimmune conditions? Read this article and you will have the answer.     1.Low Dopamine Symptoms List 2.About Dopamine 3.Dopamine and The Brain 4.Dopamine, Hormones and The Metabolism of Sugar and Fats 5.Dopamine and The Immune System 6.Dopamine Deficiency and MS 7. How To Increase Dopamine- Best Supplements, Drugs, and Therapies    1.Low Dopamine Symptoms List  : Unable to find the motivation to finish a task Losing temper/getting upset over  little things Angry, irritable, mood swings, especially  during stressful times Less social, prone to isolation Less concerned about family or friends Feeling depressed (i.e. low energy, worthlessness, hopelessness) Decreased mental flexibility  Low sex drive Sleep problems  Physical symptoms: fatigue, high blood pressure, high cholesterol, weight gain and inability to lose weight, insulin resistance or diabetes (metabolic syndrome), acid reflux, irritable bowel syndrome Self-destructive behavior (i.e. addictions) Severe dopamine deficiency: slow movement, abnormal movement, lack of coordination (as seen in Parkinson’s disease) * not all the symptoms above must be present; these symptoms may be caused by other conditions as well. This low dopamine symptoms list simply gives you an idea of what happens if you have a shortage of this neurotransmitter. It is easy to notice that dopamine deficiency and...

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